2. Signaling Pathways
  3. Epigenetics
  4. Histone Methyltransferase
  5. Histone Methyltransferase Ligand

Histone Methyltransferase Ligand

Histone Methyltransferase Isoform Comparison

Histone Methyltransferase Ligands (10):

Cat. No. Product Name Effect Purity
  • HY-78694
    5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide
    		Ligand 98.22%
    5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide is a drug intermediate for synthesis of various active compounds.
  • HY-173562
    PRMT5 ligand 2
    		Ligand 98.03%
    PRMT5 ligand 2 (Compound 38) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). PRMT5 ligand 2 can be used for synthesis MS115 (HY-173561).
  • HY-173423
    DOT1L ligand-1
    		Ligand
    DOT1L ligand-1 is a DOT1L ligand. DOT1L ligand-1 can be used as a Ligands for Target Protein for PROTAC synthesis, such as MS2133 (HY-173422).
  • HY-179351
    EZH2 ligand-1
    		Ligand
    EZH2 ligand-1 (Compound E) is an EZH2 ligand that can be used for the synthesis of PORTAC.
  • HY-181393
    EZH2 ligand-3
    		Ligand
    EZH2 ligand-3, a EZH2 ligand, is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). EZH2 ligand-3 can be used for the synthesis of PROTAC EZH2 Degrader-35 (HY-181392).
  • HY-181522
    PRMT5 ligand 3
    		Ligand
    PRMT5 ligand 3 (Compound S19) is a PRMT5 ligand that can be used for the synthesis of PROTACs, such as RAPRMT5 (HY-181521).
  • HY-181790
    DOT1L ligand-2
    		Ligand
    DOT1L ligand-2 (Compound 52) is a DOT1L ligand. DOT1L ligand-2 acts as a Ligand for Target Protein for PROTAC, which is used to develop and design degraders of PROTAC DOT1L, such as DOT1L808 (HY-181789). DOT1L ligand-2 is applicable to research related to MLL-rearranged leukemia.
  • HY-182298
    PRMT1 ligand-Linker Conjugate 1
    		Ligand
    PRMT1 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate containing a PRMT1 ligand (HY-182297) and a PROTAC linker, which recruits E3 ligases. PRMT1 ligand-Linker Conjugate 1 can be used to synthesize PROTAC PRMT1 degrader-1 (HY-182275).
  • HY-173092
    PRMT5 ligand 1
    		Ligand
    PRMT5 ligand 1 (compound 3) is the ligand for PRMT5 that can be used as target protein ligand for synthesis of PROTAC degrader MS4322 (HY-141877).
  • HY-175630
    BI-9321-C10-acid
    		Ligand
    BI-9321-C10-acid is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for NSD3 (HY-114208) and a PROTAC linker (HY-114208). BI-9321-C10-acid can be used for synthesis of PROTAC NSD3 degrader-1 (HY-155816).